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Cologuard is just not for high-possibility people, which include individuals with a private heritage of colorectal cancer and adenomas; have had a positive outcome from One more colorectal cancer screening system in the last 6 months; happen to be diagnosed using a condition connected with substantial danger for colorectal cancer including IBD, Continual ulcerative colitis, Crohn’s disease; or Use a family members record of colorectal cancer, or particular hereditary syndromes.
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Bogus positives and Bogus negatives do manifest. inside of a clinical review, 13% of individuals without the need of colorectal most cancers or State-of-the-art adenomas obtained a favourable outcome (Phony optimistic) and 8% of people with cancer obtained a negative final result (Phony adverse).
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Cologuard is meant for use with people, age forty five many years and more mature, at average danger who're regular candidates for CRC screening. Cologuard wasn't clinically evaluated for the subsequent types of individuals:
effectiveness has not been evaluated in Grown ups who are Earlier analyzed with Cologuard. Noninferiority or superiority of Cologuard programmatic sensitivity when compared with other advisable that screening techniques for CRC and AA has not been established
individuals mustn't provide a sample for Cologuard if they have got diarrhea or if they have got blood in their urine or stool (eg, from bleeding hemorrhoids, bleeding cuts or wounds on their arms, rectal bleeding, or menstruation)
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